Biospectroscopy and Interfaces Research Group

PATENTS
1. Cationic core-shell polymers, S.N. Pinto, D. Mil-Homens, N. Bernardes, A. Fialho, A. Aguiar-Ricardo, R.F. Pires, V.D.B. Bonifácio, Portuguese Patent N. 116802, 01.10.2020.

BOOKS & BOOK CHAPTERS
1. V.D.B. Bonifácio, Ovarian cancer biomarkers: Moving forward in early detection in Tumor microenvironment - The main driver of metabolic adaptation, Springer Nature, Switzerland, 2020.
2. M.A. Branco, T.P. Dias, J.P. Cotovio, C.A. V. Rodrigues, T.G. Fernandes, J.M. S. Cabral, M.M. Diogo,
3D microwell platform for cardiomyocyte differentiation of human pluripotent stem cells, Methods in Molecular Biology, Spinger Protocols, Human Press, 2020, 1-17.

ARTICLES
1. C. Pereira-Leite, S.K. Jamal, J.P. Almeida, A. Coutinho, M. Prieto, I. M. Cuccovia, C. Nunes, S. Reis, Neutral diclofenac causes remarkable changes in phosphatidylcholine bilayers: Relevance for gastric toxicity mechanisms, Mol. Pharmacol. 2020, 97, 295-303.
2. M. Martinez-Calle, M. Prieto, B. Olmeda, A. Fedorov, L.L. Loura, J. Perez-Gil, Pulmonary surfactant protein SP-B nanorings induce the multilamellar organization of surfactant complexes,
Biochim. Biophys. Acta. Biomembranes, 2020, 1861, 183216.
3. T.C.B Santos, A. Vaz, A.E. Ventura, E. M. Saied, C. Arenz, A. Fedorov, M. Prieto, L.C. Silva, Canonical and 1-deoxy(methyl) sphingoid bases: Tackling the effect of the lipid structure on membrane biophysical properties,
Langmuir, 2020, 36(21), 6007-6016.
4. C. Díaz-García, F. Hornos, A. M. Giudici, A. Cámara-Artigas, J.R. Luque-Ortega, A. Arbe, B. Rizzuti, C. Alfonso, J.K. Forwood, L. Juan, J.L. Lovanna, J. Gómez, M. Prieto, A. Coutinho, J.L. Neira, Human importin α3 and its N-terminal truncated form, without the importin-β-binding domain, are oligomeric species with a low conformational stability in solution,
Biochim. Biophys. Acta-Gen. Subjects 2020, 1864, 129609.
5. A.E. Ventura, A.R.P. Varela, T. Dingjan, T.C.B. Santos, A. Fedorov, A.H. Futerman, M. Prieto, L.C. Silva, Lipid domain formation and membrane shaping by C24-ceramide,
Biochim. Biophys. Acta-Biomembr. 2020, 1862, 183400.
6. M. Birol, A.M. Melo, Untangling the conformational polymorphism of disordered proteins associated with neurodegeneration at the single-molecule level,
Front. Mol. Neurosci. 2020, 12.
7. A.S. Miranda, P.M. Marcos, J.R. Ascenso, M.N. Berberan-Santos, R. Schurhammer, N. Hickey, S. Geremia, Dihomooxacalix[4]arene-based fluorescent receptors for anion and organic ion pair recognition,
Molecules 2020, 25, 4708.
8. S.A. Milheiro, J. Gonçalves, R.M.R.M. Lopes, M. Madureira, L. Lobo, A. Lopes, F. Nogueira, D. Fontinha, M. Prudêncio, M.F. Piedade, S.N. Pinto, P.R. Florindo, R. Moreira, Half-sandwich cyclopentadienylruthenium(II) complexes: A new antimalarial chemotype,
Inorg Chem. 2020, 59(17), 12722-12732.
9. A.I. Pimenta, D. Mil-Homens, S.N. Pinto, A.M. Fialho, Phenotypic characterization of trimeric autotransporter adhesin-defective bcaC mutant of Burkholderia cenocepacia: Cross-talk towards the histidine kinase BCAM0218,
Microbes Infect. 2020, 22(9), 457-466.
10. C.I.C. Crucho, J. Avó, A.M. Diniz, S.N. Pinto, J. Barbosa, P.O Smith, M.N. Berberan-Santos, L.O. Pålsson, F.B. Dias, TADF dye-loaded nanoparticles for fluorescence live-cell imaging,
Front. Chem. 2020, 8, 404.
11. C.I.M. Santos, L. Rodríguez-Pérez, G. Gonçalves, S.N. Pinto, M. Melle-Franco, P.A.A.P. Marques, M.A.F. Faustino, M.A. Herranz, N. Martin, M.G.P.M.S. Neves, J.M.G. Martinho, E.M.S. Maçôas, Novel hybrids based on graphene quantum dots covalently linked to glycol corroles for multiphoton bioimaging,
Carbon 2020, 166, 164-174.
12. C.I.C. Crucho, J. Avó, R. Nobuyasu R, S.N. Pinto, F. Fernandes, J.C. Lima, M.N. Berberan-Santos, F.B. Dias, Silica nanoparticles with thermally activated delayed fluorescence for live cell imaging, Mater. Sci. Eng. C 2020, 109, 110528.
13. M.M. Alves, D. Mil-Homens, S.N. Pinto, C.F. Santos, M.F. Montemor, Antagonist biocompatibilities of Zn-based materials functionalized with physiological active metal oxides,
Colloids Surf. B Biointerfaces, 2020, 191, 110990.
14. F. Baraket, B. Pedras, E. Torres, M.J. Brites, M. Dammak, M.N. Berberan-Santos, Novel phenoxazine-benzonitrile and phenothiazine-benzonitrile donor-acceptor molecules with thermally activated delayed fluorescence (TADF),
Dyes and Pigments, 2020, 175, 108114.
15. M. Outis, J.P. Leal, J. Avó, B. Monteiro, C.C.L. Pereira, A Europium(III) complex embedded in a polysulfone host matrix: A flexible film with temperature‐responsive ratiometric behaviour,
ChemPlusChem, 2020, 85, 2629-2635.
16. M. Tosolini, J. Avó, A.J. Parola, G. Balducci, P. Tecilla, Sterically encumbered 4,5‐bis(diphenylphosphino)acenaphthene ligand and its Ni(II), Pd(II), Pt(II), and Cu(I) complexes,
Eur. J. Inorg. Chem. 2020, 3859-3868.
17. C.I.C Crucho, J. Avó, A.M. Diniz, M.J.S. Gomes, Challenges in teaching organic chemistry remotely,
J. Chem. Educ. 2020, 97, 3211-3216.
18. A. Beltrán, I. Gata, C. Maya, J. Avó, J.C. Lima, C.A.T. Laia, R. Peloso, M. Outis, M.C. Nicasio, Dinuclear Cu(I) halides with terphenyl phosphines: Synthesis, photophysical studies, and catalytic applications in CuAAC reactions,
Inorg. Chem. 2020, 59, 10894-10906.
19. A.J. Moro, J. Avó, M. Malfois, F. Zaccaria, C. Fonseca-Guerra, F.J. Caparrós, L. Rodríguez, J.C. Lima, Aggregation induced emission of a new naphthyridine-ethynyl–gold(i) complex as a potential tool for sensing guanosine nucleotides in aqueous media,
Dalton Trans. 2020, 49, 171-178.
20. R.B. Restani, M.T. Tavares, R.F. Pires, P.V. Baptista, A.R. Fernandes, T. Casimiro, V.D.B. Bonifácio, A. Aguiar-Ricardo, Nano-in-micro sildenafil dry powder formulations for the treatment of pulmonary arterial hypertension disorders: The synergic effect of POxylated polyurea dendrimers, PLGA and cholesterol,
Part. Part. Syst. Charact. 2020, 37 (6).
21. A. Cruz, P. Mota, C. Ramos, R.F. Pires, C. Mendes, J. Pais, S.C. Nunes, V.D.B. Bonifácio, J. Serpa, Polyurea dendrimer folate-targeted nanodelivery of L-buthionine sulfoximine as a tool to tackle ovarian cancer chemoresistance,
Antioxidants 2020, 9, 133. Part of the special issue "When the Anticancer Strategies Modulating Oxidative Stress Meet Nanomedicine: New Perspectives".
22. R.F. Pires, A. Charas, J. Morgado, T. Casimiro, V.D.B. Bonifácio, Photodiode-like behavior of jelly dye-sensitized donor-acceptor dendrimers,
J. Appl. Pol. Sci. 2020, 137, 48635.
23. R.F. Pires, J.Conde, V.D.B. Bonifácio, Osteogenic differentiation of human mesenchymal stem cells by the single action of luminescent polyurea oxide biodendrimers,
ACS Appl. Bio Mater. 2020.
24. V.D.B. Bonifácio, S.A. Pereira, J. Serpa, J.B. Vicente, Cysteine metabolic circuitries: Druggable targets in cancer,
Br. J. Cancer 2020.
25. A.M. Ferraria, A.M. Botelho do Rego, I. Ferreira Machado, L.F. Vieira Ferreira, S. Boufi, Cotton fabrics decorated with nanostructured Ag/AgX (X:Cl,Br) as reusable solar light-mediated bactericides: A comparative study, Wafa Cheikhrouhou,
Colloids Surf. B, 2020, 196, 111342.
26. L.F. Vieira Ferreira, I. Ferreira Machado, A. Gama, F. Lochte, R. P. Socoteanu, R. Boscencu, Surface photochemical studies of nano-hybrids of A3B porphyrins and Fe3O4 silica-coated nanoparticles,
J. Photochem. Photobiol. A: Chem. 2020, 387, 112152.
27. L.F. Vieira Ferreira, L. Barros, I. Ferreira Machado, M.F.C. Pereira, T.M. Casimiro, An archaeometric study of a Late Neolithic cup and coeval and Chalcolithic ceramic sherds found in the São Paulo Cave, Almada, Portugal,
J. Raman Spectrosc. 2020, 51, 483-492.
28. L.F. Vieira Ferreira, E. Sousa, M.F.C. Pereira, S. Guerra, I. Ferreira Machado, An archaeometric study of the Phoenician ceramics found at the São Jorge Castle’s hill in Lisbon,
Ceram. Intern. 2020, 46, 7659-7666.
29. L.F. Vieira Ferreira, I. Ferreira Machado, A. Gama, R.P. Socoteanu, R. Boscencu, G. Manda, R.C. Calhelha, I.C.F.R. Ferreira, Photochemical/photocytotoxicity studies of new tetrapyrrolic structures as potential candidates for cancer theranostics,
Curr. Drug Discov. Technol. 2020, 17, 660-668.
30. A. Paul, K.K. Upadhyay, G. Backovic, A. Karmakar, L.F. Vieira Ferreira, B.S. Ljukic, M.F. Montemor, M.F.C. Guedes da Silva, A.J.L. Pombeiro, Versatility of amide-functionalized Co(II) and Ni(II) coordination polymers: From thermochromic-triggered structural transformations to supercapacitors and electrocatalysts for water splitting,
Inorg. Chem. 2020, 59(22), 16301–16318.
31. E. Lima, R.E. Boto, D. Ferreira, J.R. Fernandes, P. Almeida, L.F. Vieira Ferreira, E.B. Souto, A.M. Silva, L.V. Reis, Quinoline- and benzoselenazole-derived unsymmetrical squaraine cyanine dyes: Design, synthesis, photophysicochemical features and light-triggerable antiproliferative effects against breast cancer cell lines,
Materials, 2020, 13, 02083 1-17.
32. T.C.D. Fernandes, E. Lima, R.E. Boto, D. Ferreira, J.R. Fernandes, P. Almeida, L.F. Vieira Ferreira, A.M. Silva, L.V. Reis, In vitro phototherapeutic effects of indolenine-based mono- and dithiosquaraine cyanine dyes against Caco-2 and HepG2 human cancer cell lines,
Photodiagn. Photodyn. Ther. 2020, 31, 101844.
33. T.D. Martins, E. Lima, R.E. Boto, D. Ferreira, J.R. Fernandes, P.Almeida, L.F. Vieira Ferreira, A.M. Silva, L.V. Reis, Red and near-infrared absorbing dicyanomethylene squaraine cyanine dyes: Photophysicochemical properties and anti-tumor photosensitizing effects,
Materials 2020, 13(9), 2083.
34. Z. Ait-Touchente, A.M. Khalil, S. Simsek, S. Boufi, L.F. Vieira Ferreira, M. Rei Vilar, R. Touzani, M.M. Chehimi, Ultrasonic effect on the photocatalytic degradation of Rhodamine 6G (Rh6G) dye by cotton fabrics loaded with TiO2,
Cellulose 2020, 27, 1085-1097.
35. L. Schweitzer, A. Cunha, T. Pereira, K. Mika, A.M. Botelho do Rego, A.M. Ferraria, H. Kieburg, S. Geissler, E. Uhlmann, J. Schoon, Preclinical in iitro assessment of submicron-scale laser surface texturing on Ti6Al4V,
Materials 2020, 13, 5342.
36. I.A.S. Matias, A.P.C. Ribeiro, A.M. Ferraria, A.M. Botelho do Rego, L.M.D.R.S. Martins, Catalytic performance of a magnetic core-shell iron(II) C-scorpionate under unconventional oxidation conditions,
Nanomaterials 2020, 10(11), 2111.
37. D. Tsyganov, N. Bundaleska, J. Henriques, E. Felizardo, A. Dias, M. Abrashev, J. Kissovski, A. M. Botelho do Rego, A. M. Ferraria, E. Tatarova, Simultaneous synthesis and nitrogen doping of free-standing graphene applying microwave plasma,
Materials 2020, 13 (2020) 4213.
38. W. Cheikhrouhou, A.M. Ferraria, A.M. Botelho do Rego, I.F. Machado, L.F. Vieira Ferreira, S. Boufi, Cotton fabrics decorated with nanostructured Ag/AgX (X:Cl,Br) as reusable solar light-mediated bactericides: A comparative study,
Colloids Surf. B Biointerfaces 2020, 196, 111342.
39. A. Indekeu, E. Bailón-García, A. Fernandes, R. Baltazar, A.M. Ferraria, A.M. Botelho do Rego, M.F. Ribeiro, Synthesis of modified TiO2-based catalysts for the photocatalytic production of solar fuels from synthesis gas,
Catal. Today, 2020.
40. S.G. Meirinho, A.M. Ferraria, A.M. Botelho do Rego, A.J.S. Fernandes, A.S. Viana, J.C.S. Fernandes, M.C. Oliveira, Electrochemical properties of oxygen-enriched carbon-based nanomaterials,
J. Electroanal. Chem. 2020, 873, 114420.
41. M. Arrés, M. Salama, D. Rechena, P. Paradiso, L. Reis, M.M. Alves, A.M. Botelho do Rego, M.J. Carmezim, M.F. Vaza, A.M. Deus, C. Santos, Surface and mechanical properties of a nanostructured citrate hydroxyapatite coating on pure titanium,
J. Mech. Behav. Biomed. Mater. 2020, 108, 103794.
42. N. Bundaleska, A. Dias, N. Bundaleski, E. Felizardo, J. Henriques, D. Tsyganov, M. Abrashev, E. Valcheva, J. Kissovski, A. M. Ferraria, A. M. Botelho do Rego, A. Almeida, J. Zavašnik, U. Cvelbar, O.M.N.D. Teodoro, Th. Strunskus, E. Tatarova, Prospects for microwave plasma synthesized N-graphene in secondary electron emission mitigation applications,
Sci. Rep. 2020, 10, 13013.
43. D. Tsyganova, N. Bundaleska, A. Dias, J. Henriques, E. Felizardo, M. Abrashev, J. Kissovski, A.M. Botelho do Rego, A.M. Ferraria, E. Tatarova, Microwave plasma-based direct synthesis of free-standing N-graphene,
PCCP 2020, 22, 4772-4787.
44. M.M.A. Soliman, M.N. Kopylovich, E.C.B.A. Alegria, A.P.C. Ribeiro, A.M. Ferraria, A.M. Botelho do Rego, L.M.M. Correia, M.S. Saraiva, A.J.L. Pombeiro, Ultrasound and radiation-induced catalytic oxidation of 1-phenylethanol to acetophenone with iron-containing particulate catalysts,
Molecules 2020, 25, 740.
45. J.F.M.L. Mariano, V.G. Bessergenev, J.P. Lourenço, M. Hantusch E. Burkel, A.M. Botelho do Rego, M. Rajňák, M. Timko, P. Kopčanský, Structural and magnetic properties of P25 TiO2 nanoparticles doped by Co,
J. Magn. Magn. Mater. 2020, 501, 166442.